Friday, April 9, 2021

Alpha-gal syndrome

Amblyomma americanum, a vector for the allergy



I met someone today with Alpha-gal syndrome. He was an Eagle Scout and probably got bit by a tick while outdoors. He was one of the first people in the state of Missouri "officially" diagnosed with the condition.

Alpha-gal syndrome is a type of food allergy to red meat and other products made from mammals. In the United States, the condition most often begins when a Lone Star tick bites someone. The bite transmits a sugar molecule called alpha-gal into the person's body. In some people, this triggers an immune system reaction that later produces mild to severe allergic reactions to red meat, such as beef, pork or lamb, or other mammal products.

The Lone Star tick is found predominantly in the southeastern United States, and most cases of alpha-gal syndrome occur in this region. The tick can also be found in the eastern and south central United States. The condition appears to be spreading farther north and west, however, as deer carry the Lone Star tick to new parts of the United States. Alpha-gal syndrome also has been diagnosed in Europe, Australia and Asia, where other types of ticks carry alpha-gal molecules.

Researchers now believe that some people who have frequent, unexplained anaphylactic reactions — and who test negative for other food allergies — may be affected by alpha-gal syndrome. There's no treatment other than avoiding red meat and other products made from mammals.

Read more here.

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February 31, 1869

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